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''Combretum molle'' is widespread in dry tree and shrub savanna, often forming pure stands, from sea-level up to 2300 m altitude. It occurs on many types of soil, including rocky slopes, quartzite outcrops and termite mounts, and also on soil with high concentrations of nickel, copper or other metals. In southern Africa ''Combretum molle'' is one of the most common constituents in ''Brachystegia-Julbernardia'' (Miombo) woodland. It occurs mainly in areas with annual rainfall up to 800 mm. It tolerates partial shade and is drought and frost hardy. ''Combretum molle '' is highly fire resistant.