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''Combretum paniculatum'' is part of a species complex, including also ''Combretum microphyllum'' Klotzsch and ''Combretum platypetalum'' Laws. In some taxonomical treatments, ''Combretum microphyllum'' is considered a subspecies of ''Combretum paniculatum'' as the main difference is that it grows under drier conditions than ''Combretum paniculatum'' and is deciduous. There exists a pentamerous form of ''Combretum paniculatum'' in Ethiopia, Uganda, Kenya and Tanzania.

''Combretum fuscum'' Planch. ex Benth. occurs in the humid forest areas of tropical Africa. In central Africa a leaf maceration is drunk to treat coughs. Ground leaves are introduced vaginally to treat post-partum pain.