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''[[Gomphocarpus tomentosus]]'' Burch. occurs throughout southern Africa. In Namibia the powder of leaves and stems is used as a snuff to treat colds with nasal discharge. A decoction of the whole plant is used as a genital wash to treat venereal sores. Powder of roasted leaves is applied to wounds and venereal sores. In Botswana dried leaves are taken as an emetic; powdered roots macerated in water are taken as an emetic after poisoning. In South Africa the Tsonga people drink a root decoction to treat intestinal worms.