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There may be chemical differences between ''Adenium multiflorum'' from different provenances, as the plant is relished by animals in Zimbabwe, but in other countries it is considered highly poisonous.

Succulent shrub or small tree up to 3.5 m tall, with watery latex and with large thickened root, up to 1 m in diameter at stem base; bark shiny grey. Leaves arranged spirally, clustered at end of branchlets, simple; stipules minute or absent; petiole 3–7 mm long; blade obovate to oblong, 7.5–12.5 cm × 2–7.5 cm, base cuneate, apex acute to rounded or emarginate, apiculate or mucronate, entire, leathery, glabrous, pinnately veined with distinct lateral veins. Inflorescence a dense terminal cyme; bracts narrowly obovate, 4–6 mm × 1–3 mm. Flowers bisexual, regular, 5-merous, showy, usually appearing before the leaves; pedicel 2–4 mm long, densely hairy; sepals narrowly ovate, 6–10 mm × 2.5–3 mm, fused at base, hairy; corolla with funnel-shaped tube 2.2–4 cm × 1–1.3 cm and narrowly ovate to narrowly obovate, spreading lobes 1.3–3 cm × 1–2 cm, red, pink to white with deep pink to scarlet margins and red stripes inside the throat, hairy outside; stamens inserted near base of corolla tube, distinctly exserted, anthers forming a cone covering the pistil, base sagittate, 5–7 mm long, with long apical appendices; ovary superior, composed of 2 free carpels, glabrous, styles fused, slender, with well-developed clavuncula. Fruit consisting of 2 oblong follicles 10–18 cm long, eventually spreading at 180°, pale grey to pale grey-brown, opening by a longitudinal slit, many-seeded. Seeds linear, 10–15 mm long, very pale brown, with tufts of long dirty white to light brown hairs at both ends 2–3 cm long.

''Adenium'' comprises 5 species, which are sometimes merged into a single one, ''Adenium obesum'' (Forssk.) Roem. & Schult. ''Adenium multiflorum'' crosses readily with ''Adenium obesum'' and with other ''Adenium'' spp.

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[[Category:Medicinal plants (PROTA)]]